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Recent works (since 2018)

Shah P, Hobson CM, Cheng S, Colville MJ, Paszek MJ, Superfine R, Lammerding J. 2020. Nuclear deformation causes DNA damage by increasing replication stress. Curr Biol S0960-9822(20)31748-6.

Kuo JC, Goudge MC, Metzloff AE, Huang LT, Colville MJ, Park S, Zipfel WR, Paszek MJ. 2020. Litmus-Body: a Molecularly Targeted Sensor for Cell-Surface pH Measurements. ACS Sensors: 5(6):1555–1566.

Cheng Z., Shurer CR, Schmidt S, Gupta VK, Chuang G, Su J, Watkins AR, Shetty A, Spector JA, Hui CY, Reesink HL, Paszek MJ. 2020. The surface stress of biomedical silicones is a stimulant of cellular response. Science Advances 6(15): eaay0076.

Noble JM, Roberts LM, Vidavsky N, Chiou AE, Fischbach C, Paszek MJ, Estroff LA, Kourkoutis LF. 2020. Direct comparison of optical and electron microscopy methods for structural characterization of extracellular vesicles. J Struct Biol.: 210(1):107474

Pan H, Colville MJ, Supekar NT, Azadi P, Paszek MJ. 2019. Sequence-specific mucins for glycocalyx engineering. ACS Synth. Biol. 8(10): 2315-26.

Cox EC, Thornlow DN, Jones MA, Fuller JL, Merritt JH, Paszek MJ, Alabi CA, DeLisa MP. 2019. Antibody-Mediated Endocytosis of Polysialic Acid Enables Intracellular Delivery and Cytotoxicity of a Glycan-Directed Antibody-Drug Conjugate. Cancer Res.: 79(8):1810–1821.

Colville MJ, Park S, Zipfel WR, and Paszek MJ. High-speed device synchronization in optical microscopy with an open-source hardware control platform. Scientific Reports. 9: 1-13.

Shurer CR, Kuo JC, Roberts LM, Gandhi JG, Colville MJ, Enoki TA, Pan H, Su J, Noble JM, Hollander MJ, O'Donnell JP, Yin R, Pedram K, Möckl L, Kourkoutis LF, Moerner WE, Bertozzi CR, Feigenson GW, Reesink HL, and Paszek MJ. 2019. Physical Principles of Membrane Shape Regulation by the Glycocalyx. Cell. 177(7): 1757-1770.  Highlighted in:

  1. Godula K, Cell (2019).

  2. Strzyz P, Nature Reviews Molecular Cell Biology (2019)

  3. Faculty of 1000 Prime


Colville MJ, Park S, Zipfel WR, Paszek MJ. 2019 High-speed device synchronization in optical microscopy with an open-source hardware control platform. BioRxiv. doi:

Shurer CR, Head SE, Goudge MC, Paszek MJ. 2019. Mucin-coating technologies for protection and reduced aggregation of cellular production systems. Biotechnol Bioeng. 116(5):994-1005.

Shurer CR, Wang Y, Feeney E, Head SE, Zhang VX, Su J, Cheng Z, Stark MA, Bonassar LJ, Reesink HL, Paszek MJ. 2019. Stable recombinant production of codon-scrambled lubricin and mucin in human cells. Biotechnol Bioeng. 116(6):1292-1303.

Gandhi JG, Koch DL, and Paszek MJ. 2019. Equilibrium Modeling of the Mechanics and Structure of the Cancer Glycocalyx. Biophys J. 116(4): 694-708.

Kuo JC, Gandhi J, Zia R, Paszek MJ. 2018. Physical Biology of the Cancer Cell Glycocalyx.  Nature Physics.  14: 658-669.

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